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Evaluation of p16 in Epithelial Ovarian Cancer for a 10-Year Study in Northeast China: Significance of HPV in Correlation with PD-L1 Expression.

Xin-Xin YangQi YouGuodong YaoJingshu GengRong MaHong-Xue Meng
Published in: Cancer management and research (2020)
Our study demonstrates that HPV infection and p16 overexpression is significantly associated with PD-LI expression in EOC, through the cooperative roles of dendritic cells (DCs) and IFN-γ, which may represent a promising strategy for therapeutic intervention in EOC.
Keyphrases
  • dendritic cells
  • randomized controlled trial
  • immune response
  • cell proliferation
  • regulatory t cells