Association of increased hepatic insulin clearance and change in serum triglycerides or β-hydroxybutyrate concentration via the sodium/glucose-cotransporter 2 inhibitor tofogliflozin.
Yasuhiro MatsubayashiAlkihiro YoshidaHideki SuganamiTaeko OsawaKazuo FurukawaHiroshi SuzukiMayuko Harada YamadaShiro TanakaKohei KakuYasuhiro MatsubayashiPublished in: Diabetes, obesity & metabolism (2020)
Increased HICCIR was significantly associated with reduced TG via TOFO and contributed to the greater increase in BHB compared with placebo in addition to the correction of hyperinsulinaemia.