HIV pretreatment drug resistance among cisgender MSM and transgender women from Lima, Peru.
William L TrebelcockJavier R LamaAnn DuerrHugo SanchezRobinson CabelloTrupti GiladaPatricia SeguraSari L ReisnerKenneth H MayerJames MullinsRachel Bender IgnacioPublished in: Journal of the International AIDS Society (2020)
Prevalence of NNRTI resistance in three studies of ART-naïve MSM and TW in Lima, Peru reaches 10%. Because our study reports PDR in a population in which most acquired HIV recently, the overall prevalence of PDR, including previously treated persons, is likely underestimated. These results underscore the need for a nationally representative survey of PDR in Peru and consideration of non-NNRTI anchored first-line ART options. This study also represents the first evaluation of PDR in cis-MSM versus TW in South America, and demonstrates that, although TW are at higher risk of acquiring HIV, they are at similar risk of acquiring a virus with resistance mutations.
Keyphrases
- hiv testing
- men who have sex with men
- antiretroviral therapy
- hiv infected
- hiv positive
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- risk factors
- type diabetes
- polycystic ovary syndrome
- metabolic syndrome
- south africa
- cross sectional
- emergency department
- skeletal muscle
- electronic health record
- breast cancer risk