A Serological Biomarker of Laminin Gamma 1 Chain Degradation Reflects Altered Basement Membrane Remodeling in Crohn's Disease and DSS Colitis.

Majken LindholmAntonio Di SabatinoTina Manon-JensenGiuseppe MazzaGunvor I MadsenPaolo GiuffridaMassimo PinzaniAleksander KragMorten A KarsdalJens KjeldsenJoachim H Mortensen

Published in: Digestive diseases and sciences (2021)

Increased serum LG1M in active and inactive CD patients supports the evidence of altered LM expression in both inflamed and non-inflamed tissue. Moreover, lower LG1M levels in the early healing phase of DSS-induced colitis may reflect ongoing mucosal repair.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
poor prognosis
peritoneal dialysis
prognostic factors
ulcerative colitis
patient reported outcomes