Impact of pre-operative weight loss on non-alcoholic fatty liver disease histopathology and insulin resistance in individuals undergoing bariatric surgery: a propensity matched cross-sectional comparison.

Fábio Henrique Ribeiro Maldonado Paulo Ferreira Mega Carlos Wustemberg Germano Luana Leite Castilho Dias Guilherme Hoverter Callejas Martinho Antônio Gestic Martinho Antonio Gestic Felipe David Mendonça Chaim Francisco Callejas-Neto Élinton Adami Chaim Everton Cazzo

Published in: Sao Paulo medical journal = Revista paulista de medicina (2023)

Pre-operative WL was significantly associated with lower frequencies of macro- and mi- crovesicular steatosis, portal inflammation, and lower glycemia, indicating an association between the recent trajectory of body weight and histological aspects of NAFLD.

Keyphrases

body weight
bariatric surgery
weight loss
cross sectional
obese patients
roux en y gastric bypass
gastric bypass
oxidative stress
insulin resistance
high fat diet
type diabetes
metabolic syndrome
liver fibrosis
body mass index
glycemic control
physical activity
skeletal muscle
high fat diet induced