A case report: pause and consider the late complications of heart transplantation.

Features that make this case study unique include the late onset and location of the malignancy, the absence of Epstein-Barr virus involvement, and asystole that was potentially neurologically mediated and induced by a brain space occupying mass. This case offers insight into potential late parasympathetic reinnervation of transplanted hearts, adds to the growing literature regarding the connection between the brain and the heart, and reviews potential complications in patients with a remote history of heart transplantation.