Immune checkpoint inhibitor therapy for advanced cutaneous squamous cell carcinoma in Australia: a retrospective real world cohort study.

Luke S McLeanAnnette M LimMathias BresselJenny LeeRahul LadwaAlexander D GuminskiBrett HughesSamantha BowyerKaren BriscoeSamuel HarrisCraig KukardRob ZielinskiMuhammad AlamgeerMatteo CarlinoJeremy MoJohn J ParkMuhammad A KhattakFiona DayDanny Rischin

Published in: The Medical journal of Australia (2024)

In our retrospective study, the effectiveness and toxicity of ICI therapy were similar to those determined in clinical trials. Our findings suggest that ICIs could be effective and well tolerated by people with advanced CSCC who are ineligible for clinical trials.

Keyphrases

clinical trial
squamous cell carcinoma
randomized controlled trial
phase ii
systematic review
oxidative stress
open label
lymph node metastasis
study protocol
double blind
bone marrow
radiation therapy