Exploring pre-surgery donor-specific antibodies in the context of organ shortage in liver transplant.
Savio George BarretoMark E Brooke-SmithEu Ling NeoPaul DolanRichard LeibbrandtTim EmeryRobert CarrollAlan WiggJohn W ChenPublished in: Langenbeck's archives of surgery (2019)
AMR following LT is uncommon. A positive DSA pre-transplant does not imply a definite risk of AMR. Also, there does not exist a significant interaction in time between DSA expression and serum bilirubin or transaminase levels. Until there emerges evidence to the contrary, it appears reasonable to consider DSA-positive donors within the broad context of marginal donors in the context of a worldwide shortage of LT donor allografts.