hsa_circ_0001275 Is One of a Number of circRNAs Dysregulated in Enzalutamide Resistant Prostate Cancer and Confers Enzalutamide Resistance In Vitro.

Marvin C J LimAnne-Marie BairdJohn GreeneCiara McNevinKarine RonanPetar PodlesniyOrla SheilsSteven G GrayRay S McDermottStephen P Finn

Published in: Cancers (2021)

Our data suggest that increased levels of hsa_circ_0001275 contribute to enzalutamide resistance. hsa_circ_0001275 plasma expression showed a trend that mirrors the PSA level at specific disease time points, indicating that circRNAs mirror disease recurrence and burden and may be associated with enzalutamide resistance.

Keyphrases

prostate cancer
radical prostatectomy
poor prognosis
risk factors
big data
artificial intelligence
data analysis