Endoscopic and Histological Placebo Rates in Crohn's Disease Clinical Trials: A Systematic Review and Meta-analysis.
Sudheer K VuyyuruTran M NguyenMalcolm HoganTim RaineNurulamin M NoorNeeraj NarulaBram VerstocktBrian G FeaganSiddharth SinghChristopher MaVipul JairathPublished in: Inflammatory bowel diseases (2023)
Endoscopic placebo rates vary according to trial phase and prior biologic exposure. These contemporary data will serve to inform CD trial design, sample size calculation, and end point selection for future trials.