Intrathymic Plasmablasts Are Affected in Patients With Myasthenia Gravis With Active Disease.
Yohei YamamotoNaoko MatsuiAkiyuki UzawaYukiko OzawaTetsuya KanaiFumiko OdaHiroyuki KondoIzumi OhigashiHiromitsu TakizawaKazuya KondoMikio SuganoTakashi KitaichiHiroki HataRyuji KajiSatoshi KuwabaraTakashi YamamuraYuishin IzumiPublished in: Neurology(R) neuroimmunology & neuroinflammation (2021)
Our findings confirmed a correlation between increased frequency of intrathymic plasmablasts and disease activity before thymectomy. We postulate that activated intrathymic plasmablasts endow pathogenic capacity in MG.