Periostin regulates LPS-induced apoptosis via Nrf2/HO-1 pathway in periodontal ligament fibroblasts.

Yujun Jiang Panpan YangCongshan LiYupu Lu Yuying Kou Hongrui Liu Jie Guo Minqi Li

Published in: Oral diseases (2022)

Lipopolysaccharide induced apoptosis in PDLFs by inhibiting periostin expression and thus Nrf2/HO-1 pathway, indicating that periostin could be a potential therapeutic target for periodontitis.

Keyphrases

induced apoptosis
oxidative stress
signaling pathway
endoplasmic reticulum stress
pi k akt
inflammatory response
poor prognosis
toll like receptor
lps induced
long non coding rna
immune response