Has the reporting quality of published randomised controlled trial protocols improved since the SPIRIT statement? A methodological study.

Zet Wei TanAidan Christopher TanTom LiIan HarrisJustine M NaylorMichiel SiebeltJasper van TielMarina PinheiroLaura HarrisKira ChamberlainSam Adie

Published in: BMJ open (2020)

The overall reporting quality of RCT protocols has significantly improved since the SPIRIT statement, although a substantial proportion of individual checklist items remain poorly reported. Continued and concerted efforts are required by journals, editors, reviewers and investigators to improve the completeness and transparency of RCT protocols.

Keyphrases

quality improvement
adverse drug
emergency department
randomized controlled trial
systematic review
clinical trial
meta analyses