Cardiac Involvement by Human Herpesvirus 8-Positive Diffuse Large B-Cell Lymphoma: An Unusual Presentation in a Patient with Human Immunodeficiency Virus.
Elena M FenuMichael W BeatyTiffany E O'NeillStacey S O'NeillPublished in: Case reports in pathology (2022)
Human immunodeficiency virus (HIV) infection predisposes patients to the development of lymphomas, both due to immune suppression and coinfection with viruses with oncogenic potential. Coinfection with human herpesvirus 8 (HHV8) in particular has been associated with the development of aggressive lymphomas, including primary effusion lymphoma and diffuse large B-cell lymphoma (DLBCL). Herein, we report an unusual case of HHV8-positive DLBCL with extensive cardiac involvement which was diagnosed at autopsy in a patient with long-standing untreated HIV infection.
Keyphrases
- diffuse large b cell lymphoma
- human immunodeficiency virus
- antiretroviral therapy
- epstein barr virus
- hepatitis c virus
- hiv infected
- endothelial cells
- hiv positive
- hiv aids
- end stage renal disease
- case report
- induced pluripotent stem cells
- left ventricular
- ejection fraction
- newly diagnosed
- chronic kidney disease
- pluripotent stem cells
- prognostic factors
- peritoneal dialysis
- patient reported outcomes
- hiv testing