Initial experimental experience of triple-knockout pig red blood cells as potential sources for transfusion in alloimmunized patients with sickle cell disease.
Takayuki YamamotoMohamed H BikhetMarisa B MarquesHuy Q NguyenYehua CuiMariyam JavedSyed Sikandar RazaDavid AyaresHayato IwaseDavid K C CooperHidetaka HaraPublished in: Transfusion (2021)
In conclusion, (1) in the present limited study, no antibodies were detected that cross-reacted with TKO pRBCs, and (2) TKO pigs may possibly be an alternate source of RBCs in an emergency if no human RBCs are available.