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What have we learned on pre, very early, and early systemic sclerosis microcirculatory pathophysiology? A scoping review.

Joana CaetanoLuís Monteiro RodriguesJosé Delgado Alves
Published in: Autoimmunity reviews (2024)
Although different molecular expression patterns and signaling pathways related to microvascular dysfunction in pre-SSc, VEDOSS, and early SSc were identified, additional prospective longitudinal studies and combined work with functional evaluation of peripheral skin perfusion are needed.
Keyphrases
  • systemic sclerosis
  • interstitial lung disease
  • poor prognosis
  • signaling pathway
  • magnetic resonance
  • cell proliferation
  • rheumatoid arthritis
  • single molecule