A potent multifunctional ZIF-8 nanoplatform developed for colorectal cancer therapy by triple-delivery of chemo/radio/targeted therapy agents.

Sonia IranpourAhmad Reza BahramiMahdieh DayyaniAmir Sh Saljooghi Maryam M Matin

Published in: Journal of materials chemistry. B (2024)

The combination of Apt-PEG-DOX/ZIF-8@GQD with RT as a multimodal therapy approach demonstrated promising potential for the targeted treatment of CRC and enhancing therapeutic effectiveness. The co-delivery of DOX and GQD using this nano-platform holds great promise for improving the outcome of CRC treatment.

Keyphrases

cancer therapy
drug delivery
photodynamic therapy
randomized controlled trial
combination therapy
stem cells
mesenchymal stem cells
deep learning
big data
replacement therapy
climate change
chemotherapy induced