Mechanism of norcantharidin intervention in gastric cancer: analysis based on antitumor proprietary Chinese medicine database, network pharmacology, and transcriptomics.
Yiyan ZhaiFanqin ZhangJiying ZhouChuanqi QiaoZhengsen JinJingyuan ZhangChao WuRui ShiJiaqi HuangYifei GaoSiyu GuoHaojia WangKeyan ChaiXiaomeng ZhangTieshan WangXiaoguang ShengXinkui LiuJia-Rui WuPublished in: Chinese medicine (2024)
Norcantharidin, as an effective component of anti-tumor pCm, exerts its therapeutic effects on GC by influencing biological processes such as cell adhesion, migration, and inflammation. This study provides a foundation and research strategy for the post-marketing re-evaluation of antitumor pCms.