BTK inhibition is a potent approach to block IgE-mediated histamine release in human basophils.

Dubravka SmiljkovicK BlattG StefanzlY DorofeevaC SkrabsM Focke-TejklW R SperrU JaegerRudolph ValentaP Valent

Published in: Allergy (2017)

BTK-targeting drugs are potent inhibitors of IgE-dependent histamine release in human basophils. The clinical value of BTK inhibition in the context of allergic diseases remains to be determined.

Keyphrases

tyrosine kinase
endothelial cells
induced pluripotent stem cells
pluripotent stem cells
anti inflammatory