Clinical Outcomes and Effectiveness of CRLX101 for Solid Tumors: A Systematic Review and Meta-analysis.

Nahal Shamaeizadeh Erfan Sadeghi Jaleh Varshosaz

Published in: Current medicinal chemistry (2024)

Our meta-analysis shows that CRLX101 outperforms camptothecin in PFS despite its inferior OS. Unresolved pharmacology limits carrier-mediated drug therapeutic application. Carrier-mediated dosages may differ from normal formulations because they are rarely studied.

Keyphrases

systematic review
randomized controlled trial
meta analyses
case control
electronic health record