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Now you see me, now you don't: Isolated central nervous system recurrence of CD19-negative diffuse large B-cell lymphoma following CD19-directed CAR T-cell treatment.

Hamza Numan GokozanMadhu M OusephJose V Scarpa CarnielloKoen Van BesienSanjay S Patel
Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2022)
The authors discuss a case of CD19-negative diffuse large B-cell lymphoma with central nervous system relapse following CD19-directed CAR T-cell treatment. Absence of CD19 expression by the tumour cells presented a challenge for flow cytometry evaluation.
Keyphrases
  • diffuse large b cell lymphoma
  • epstein barr virus
  • flow cytometry
  • poor prognosis
  • oxidative stress
  • cell proliferation
  • cell death
  • long non coding rna