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Protocol paper: kainic acid excitotoxicity-induced spinal cord injury paraplegia in Sprague-Dawley rats.

Anam AnjumYt Jun CheahMuhammad Da'in YazidMuhammad Fauzi DaudJalilah IdrisMin Hwei NgAmaramalar Selvi NaickerOhnmar Htwe IsmailRamesh Kumar Athi KumarGeok Chin TanYin Ping WongMohd Kaisan MahadiYogeswaran Lokanathan
Published in: Biological research (2022)
Kainic acid intra-spinal injection at the concentration of 0.05 mM, and rate 10 µL/min, is an effective method create spinal injury in rats, however more potent concentrations of kainic acid need to be studied in order to create severe spinal injuries.
Keyphrases
  • spinal cord
  • spinal cord injury
  • randomized controlled trial
  • temporal lobe epilepsy
  • neuropathic pain
  • early onset
  • oxidative stress
  • diabetic rats
  • anti inflammatory