Comparative In Silico Analysis of Ultra-Hypofractionated Intensity-Modulated Photon Radiotherapy (IMRT) Versus Intensity-Modulated Proton Therapy (IMPT) in the Pre-Operative Treatment of Retroperitoneal Sarcoma.
Emile GogineniHao ChenAlexandra C IstlFabian M JohnstonAmol NarangCurtiland DevillePublished in: Cancers (2023)
IMPT maintained target coverage while significantly reducing the dose to adjacent OARs and integral dose compared to IMRT. A prospective trial treating RPS with pre-operative ultra-hypofractionated IMPT at our institution is currently being pursued.
Keyphrases
- radiation therapy
- high resolution
- early stage
- clinical trial
- study protocol
- locally advanced
- molecular docking
- radiation induced
- phase iii
- brain metastases
- randomized controlled trial
- small cell lung cancer
- healthcare
- phase ii
- combination therapy
- living cells
- affordable care act
- open label
- molecular dynamics simulations