Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathy.

Jeffrey D LebensburgerInmaculada AbanBrandi PernellMalgorzata KasztanDaniel I FeigLee M HilliardDavid J Askenazi

Published in: American journal of hematology (2019)

Hyperfiltration precedes the development of persistent proteinuria in pediatric SCA patients. Intervention strategies should target lowering eGFR during early childhood.

Keyphrases

end stage renal disease
small cell lung cancer
randomized controlled trial
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
peritoneal dialysis
epidermal growth factor receptor
tyrosine kinase
young adults