Effectiveness of NLRP3 Inhibitor as a Non-Hormonal Treatment for ovarian endometriosis.

Mayuko MurakamiSatoko OsukaAyako MuraokaShotaro Hayashinull BayasulaYukiyo KasaharaReina SoneharaYumi HariyamaKanako ShinjoHideaki TanakaNatsuki MiyakeSayako YoshitaNatsuki NakanishiTomoko NakamuraMaki GotoHiroaki Kajiyama

Published in: Reproductive biology and endocrinology : RB&E (2022)

These results indicated that NLRP3/IL-1β is involved in the pathogenesis of endometriosis and that NLRP3 inhibitors may be useful for suppressing OE and improving the function of ovaries with endometriosis.

Keyphrases

nlrp inflammasome
randomized controlled trial
systematic review
type diabetes
polycystic ovary syndrome
combination therapy
adipose tissue
insulin resistance