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FOXO1 Alleviates Liver Ischemia-reperfusion Injury by Regulating the Th17/Treg Ratio through the AKT/Stat3/FOXO1 Pathway.

Hao-Zhen RenSen-Zhe XiaXue-Qian QinAn-Yin HuJing-Lin Wang
Published in: Journal of clinical and translational hepatology (2022)
Liver IRI induced Th17/Treg imbalance. Upregulation of FOXO1 reversed the imbalance and alleviated liver inflammation.
Keyphrases
  • signaling pathway
  • transcription factor
  • cell proliferation
  • ischemia reperfusion injury
  • pi k akt
  • oxidative stress
  • diabetic rats
  • high glucose
  • poor prognosis
  • endothelial cells