DNA methylation analysis within the IL2RA gene promoter in youth with autoimmune thyroid disease.
Ioannis KyrgiosAikaterini FragouEleni P KotanidouKonstantina MouzakiSmaragda EfraimidouGeorgios TzimagiorgisAssimina Galli-TsinopoulouPublished in: European journal of clinical investigation (2020)
The observed DNA hypomethylation in the IL2RA gene promoter in patients with GD might be related to its increased expression, thus contributing to the etiopathogenesis of GD in childhood and adolescence.
Keyphrases
- dna methylation
- genome wide
- copy number
- gene expression
- rheumatoid arthritis
- transcription factor
- poor prognosis
- disease activity
- depressive symptoms
- mental health
- genome wide identification
- physical activity
- multiple sclerosis
- circulating tumor
- ankylosing spondylitis
- single molecule
- cell free
- systemic sclerosis
- drug induced
- interstitial lung disease
- binding protein
- systemic lupus erythematosus
- genome wide analysis