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Vitronectin-activated αvβ3 and αvβ5 integrin signalling specifies haematopoietic fate in human pluripotent stem cells.

Jun ShenYaoyao ZhuShuo ZhangShuzhen LyuCuicui LyuZicen FengDixie L HoyleZack Z WangTao Cheng
Published in: Cell proliferation (2021)
The established VTN-based monolayer system of haematopoietic differentiation of hPSCs presents a valuable platform for further investigating niche signals involved in human haematopoietic development.
Keyphrases
  • pluripotent stem cells
  • endothelial cells
  • induced pluripotent stem cells
  • single cell
  • cell adhesion