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Using known drug interactions to manage supratherapeutic calcineurin inhibitor concentrations.

Nicholas W LangeDavid M SalernoKaren BergerDemetra S Tsapepas
Published in: Clinical transplantation (2017)
There is a paucity of published data on the use of CYP450 enzyme inducers for the management of supratherapeutic CNI concentrations. While routine use of this approach cannot be recommended, thorough risk-benefit analyses should be performed in the management of each such clinical scenario.
Keyphrases
  • electronic health record
  • randomized controlled trial
  • big data
  • systematic review
  • machine learning
  • meta analyses