Using known drug interactions to manage supratherapeutic calcineurin inhibitor concentrations.
Nicholas W LangeDavid M SalernoKaren BergerDemetra S TsapepasPublished in: Clinical transplantation (2017)
There is a paucity of published data on the use of CYP450 enzyme inducers for the management of supratherapeutic CNI concentrations. While routine use of this approach cannot be recommended, thorough risk-benefit analyses should be performed in the management of each such clinical scenario.