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Functional, imaging, and respiratory evaluation (FIRE) of patients post-hospitalization for COVID-19: protocol for a pilot observational study.

Kirby P MayerJessica A PalakshappaIthan Daniel PeltanJames S AndrewStephanie J GundelNancy J RingwoodJeffrey MckeehanAluko A HopeAngela J RogersMichelle BiehlDouglas L HaydenEllen CaldwellOmar MehkriDavid J LynchEllen L BurhamCatherine L HoughSarah E Jolleynull null
Published in: Pilot and feasibility studies (2022)
Strengths: First US-based multicenter cohort of pulmonary and functional outcomes in patients previously hospitalized for COVID-19 infection Longitudinal biospecimen measurement allowing for biologic phenotyping of abnormalities Geographically diverse cohort allowing for a more generalizable understanding of post-COVID pulmonary sequela Limitations: Selected cohort given proximity to a participating center Small cohort which may be underpowered to identify small changes in pulmonary function.
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