Circulating tumor cell-related transcripts in blood as prognostic biomarkers of early recurrence after liver resection for colorectal metastases.
Felice GiulianteElena PanettieriFrancesco ArditoAgostino De RoseKrizia PocinoChiara AutilioCarmela PaolilloEttore Domenico CapoluongoPublished in: The International journal of biological markers (2019)
Blood carcinoembryonic antigen-mRNA absolute copy number overtime variation can represent a valid early predictor of relapse after liver resection in colorectal liver metastases patients. Prospective studies, in the context of large clinical trials, will provide further data to also qualify ERCC1 as a predictive biomarker for decisions on therapeutic strategies.
Keyphrases
- copy number
- liver metastases
- clinical trial
- circulating tumor
- mitochondrial dna
- end stage renal disease
- ejection fraction
- chronic kidney disease
- newly diagnosed
- genome wide
- single cell
- circulating tumor cells
- peritoneal dialysis
- electronic health record
- cell therapy
- randomized controlled trial
- cell free
- big data
- gene expression
- bone marrow
- mesenchymal stem cells
- binding protein
- case control
- patient reported
- artificial intelligence
- study protocol
- free survival
- double blind