Dendritic cell-based immunotherapy: a potential player in oral cancer therapeutics.
Ruby DwivediRahul PandeyShaleen ChandraDivya MehrotraPublished in: Immunotherapy (2023)
Background & aim: Dendritic cell (DC)-based immunotherapy modulates a patient's immune system for recognition and subsequent removal of tumor cells. DC-mediated anticancer therapy has been considered in several studies/ongoing trials for multiple types of cancer. Our aim is to describe the potential and current status of DC-based immunotherapy in oral cancer therapeutics. Materials & methods: An internet-based literature search with relevant search terms from 2012 to 2022 post-screening resulted in 58 articles that were considered for systematic review. Results & conclusion: Evaluation of DC based immunotherapy exploiting the critical immune cells in well-equipped laboratories with adequately trained and skilled experts along with a synergistic approach that is affordable and approachable to the patients can prove as an efficient anticancer therapy.
Keyphrases
- dendritic cells
- systematic review
- regulatory t cells
- immune response
- current status
- small molecule
- meta analyses
- newly diagnosed
- randomized controlled trial
- prognostic factors
- case report
- human health
- papillary thyroid
- mesenchymal stem cells
- squamous cell
- squamous cell carcinoma
- cancer therapy
- social media
- resistance training
- stem cells
- childhood cancer