Methylation of PCDH19 predicts poor prognosis of hepatocellular carcinoma.

Ting ZhangGuiwen GuanTingting ChenJingling JinLichun ZhangMingjie YaoXuewei QiJun ZouJiacheng ChenFengmin LuXiangmei Chen

Published in: Asia-Pacific journal of clinical oncology (2018)

PCDH19 expression was downregulated in HCC, which was mediated at least in part by promoter hypermethylation. PCDH19 hypermethylation might present a potential prognostic marker in HCC patients.

Keyphrases

poor prognosis
long non coding rna
end stage renal disease
dna methylation
ejection fraction
newly diagnosed
chronic kidney disease
gene expression
prognostic factors
peritoneal dialysis
transcription factor
genome wide
risk assessment
patient reported outcomes