Blood transcriptome analysis of patients with uncomplicated bacterial infection and sepsis.
Velma HerwantoBenjamin TangYa WangMaryam ShojaeiMarek NalosAmith ShettyKevin LaiAnthony S McLeanKlaus SchughartPublished in: BMC research notes (2021)
The data presented here consists of raw and processed transcriptome data obtained by next generation RNA sequencing from 105 peripheral blood samples from patients with uncomplicated infections, patients who developed sepsis, septic shock patients, and healthy controls. It is provided as raw sequenced reads and as normalized log2 transformed relative expression levels. This data will allow performing detailed analyses of gene expression changes between uncomplicated infections and sepsis patients, such as identification of differentially expressed genes, co-regulated modules as well as pathway activation studies.
Keyphrases
- septic shock
- gene expression
- end stage renal disease
- newly diagnosed
- intensive care unit
- ejection fraction
- chronic kidney disease
- acute kidney injury
- peripheral blood
- prognostic factors
- peritoneal dialysis
- single cell
- poor prognosis
- dna methylation
- machine learning
- data analysis
- patient reported
- bioinformatics analysis