Differences in outcomes between oral anticoagulation "new starters" and "switchers" in patients with nonvalvular atrial fibrillation: A pooled analysis of the AMADEUS and BOREALIS trials.
Ying BaiAlena ShantsilaGregory Yoke Hong LipPublished in: Journal of arrhythmia (2019)
In this post hoc analysis of clinical trial patients with AF, "new starters" and "switchers" for VKA initiation had nonstatistically significant rates of trial-adjudicated thromboembolism, major bleeding, and all-cause mortality.
Keyphrases
- atrial fibrillation
- clinical trial
- phase iii
- phase ii
- oral anticoagulants
- study protocol
- catheter ablation
- left atrial
- open label
- left atrial appendage
- direct oral anticoagulants
- double blind
- heart failure
- percutaneous coronary intervention
- randomized controlled trial
- acute coronary syndrome
- metabolic syndrome
- weight loss