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Diabetes Management in Chronic Kidney Disease: Synopsis of the KDIGO 2022 Clinical Practice Guideline Update.

Sankar D NavaneethanSophia ZoungasM Luiza CaramoriJuliana Chung Ngor ChanHiddo J Lambers HeerspinkClint HurstAdrian LiewErin Donelly MichosWasiu A OlowuTami SaduskyNikhil TandonKatherine R TuttleChristoph WannerKaty G WilkensJonathan C CraigDavid J TunnicliffeMarcello TonelliMichael CheungAmy EarleyEllen BurgessIan H de BoerKamlesh Khunti
Published in: Annals of internal medicine (2023)
The updated guideline includes 13 recommendations and 52 practice points for clinicians caring for patients with diabetes and chronic kidney disease (CKD). A focus on preserving kidney function and maintaining well-being is recommended using a layered approach to care, starting with a foundation of lifestyle interventions, self-management, and first-line pharmacotherapy (such as sodium-glucose cotransporter-2 inhibitors) demonstrated to improve clinical outcomes. To this are added additional drugs with heart and kidney protection, such as glucagon-like peptide-1 receptor agonists and nonsteroidal mineralocorticoid receptor antagonists, and interventions to control risk factors for CKD progression and cardiovascular events, such as blood pressure, glycemia, and lipids.
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