Impact of the COVID-19 Pandemic on Conduct and Results of CLEAR Outcomes Trial.
Abhayjit SinghLuke J LaffinAshish SarrajuA Michael LincoffStephen J NichollsLeAnne BloedonWilliam J SasielaNa LiPaula RobinsonStephanie KellyDenise MasonSteven E NissenPublished in: Clinical cardiology (2024)
The CLEAR Outcomes trial continued uninterrupted throughout the COVID-19 pandemic. Certain trial endpoints may have been impacted by the pandemic. Specifically, the classification of undetermined deaths as CV deaths may have attenuated the effect of BA on key efficacy endpoints.