Immunosenescence profile and expression of the aging biomarker (p16INK4a) in testicular cancer survivors treated with chemotherapy.
Maria T BourlonHugo E VelazquezJuan HinojosaLuis OrozcoRicardo Rios-CorzoGuadalupe LimaLuis LlorenteDiego F Hernandez-RamirezFrancisco J Valentin-CortezIrene Medina-RangelYemil Atisha-FregosoPublished in: BMC cancer (2020)
In this exploratory study, TCS showed increased expression of CDKN2A/p16INK4a and a lymphocyte phenotype that has been associated with immunosenescence. Further studies are warranted to define the clinical implications of these alterations in TCS.