Immune cell infiltration and inflammatory landscape in primary brain tumours.

Amalia LuceMarianna AbateGiosuè ScognamiglioMarco MontellaDomenico IervolinoSevero CampioneAnnabella Di MauroOrlando SepeVincenzo GigantinoMadhura S TathodeGerardo FerraraRoberto MonacoGianfranco De DominicisGabriella MissoVittorio GentileRenato FrancoSilvia ZappavignaMichele Caraglia

Published in: Journal of translational medicine (2024)

Our data have revealed that there is a positive and significant correlation between the expression of 5-LOX and GzmB, both at RNA and protein level. Further evaluation is needed to understand the interplay of 5-LOX and immune infiltration in glioma progression.

Keyphrases

single cell
poor prognosis
binding protein
low density lipoprotein
electronic health record
white matter
resting state
oxidative stress
big data
multiple sclerosis
cerebral ischemia
machine learning
data analysis