Upregulation of hsa_circ_0004812 promotes COVID-19 cytokine storm via hsa-miR-1287-5p/IL6R, RIG-I axis.

Elham MohammadisoleimaniZahra FirooziMohammad Mehdi Naghizadeh Ali GhanbariasadBabak PezeshkiYousef GholampourEbrahim MirzaeiMohamadhosain SiminMahsa SalianiAli MoravejZolfaghar ArmoonYaser Mansoori

Published in: Journal of clinical laboratory analysis (2022)

The results of this in-vitro and in silico study show that hsa_circ_0004812/hsa-miR-1287-5p/IL6R, RIG-I can play an important role in the outcome of COVID-19.

Keyphrases

coronavirus disease
sars cov
poor prognosis
molecular docking
respiratory syndrome coronavirus
signaling pathway
molecular dynamics simulations