Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (the COOL trial): study protocol for a randomized controlled trial.

Andrew W KirkpatrickFederico CoccoliniLuca AnsaloniDerek J RobertsMatti TolonenJessica L McKeeAri LeppaniemiPeter FarisChristopher J DoigFausto CatenaTimothy FabianCraig N JenneOsvaldo ChiaraPaul KubesBraden MannsYoram KlugerGustavo P FragaBruno M PereiraJose J DiazMichael SugrueErnest E MooreJianan RenChad G BallRaul CoimbraZsolt J BaloghFikri M Abu-ZidanElijah DixonWalter BifflAnthony MacLeanIan BallJohn DroverPaul B McBethJuan G Posadas-CallejaNeil G ParrySalomone Di SaverioCarlos A OrdonezJimmy XiaoMassimo Sartellinull null

Published in: World journal of emergency surgery : WJES (2018)

ClinicalTrials.gov, NCT03163095.

Keyphrases

acute kidney injury
intensive care unit
minimally invasive
study protocol
randomized controlled trial
phase iii
phase ii
septic shock