Establishment of a 3D In Vitro Model to Accelerate the Development of Human Therapies against Corneal Diabetes.

Shrestha PriyadarsiniAkhee Sarker-NagTyler G RowseyJian-Xing MaDimitrios Karamichos

Published in: PloS one (2016)

DM has significant effects on physiological and clinical aspects of the human cornea. The benefits in developing and fully characterizing our 3D in vitro model are enormous and might provide clues for the development of novel therapeutics.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells
small molecule
glycemic control
metabolic syndrome
insulin resistance