Decreased Endometrial IL-10 Impairs Endometrial Receptivity by Downregulating HOXA10 Expression in Women with Adenomyosis.

Junxia WangChenyang HuangRuiwei JiangYali DuJianjun ZhouYue JiangQiang YanJun XingXiaoni HouJidong ZhouHaixiang Sun Gui-Jun Yan

Published in: BioMed research international (2018)

Both IL-10 and HOXA10 levels in the endometrium are significantly reduced in women with adenomyosis compared with those in control women. The phosphorylation of STAT3 has been proven to be a critical mediator between IL-10 and HOXA10, which may play critical roles in embryo implantation.

Keyphrases

long non coding rna
long noncoding rna
poor prognosis
endometrial cancer
pregnancy outcomes
cell proliferation
type diabetes
adipose tissue
binding protein
metabolic syndrome
skeletal muscle