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Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma.

Xue ChengXiaosheng TanWei WangZiyao ZhangRong-Fei ZhuMi WuMingyu LiYiqing ChenZhihui LiangPeng ZhuXiongwen WuXiufang Weng
Published in: Cancer research (2023)
Patients with HBV-related HCC exhibit a cell senescence-associated dysregulation of invariant natural killer cells that is related to altered lipid metabolism and accumulated LCACs in tumor tissue.
Keyphrases
  • natural killer cells
  • dna damage
  • endothelial cells
  • hepatitis b virus
  • stress induced
  • single cell
  • cell therapy
  • liver failure
  • fatty acid
  • stem cells
  • oxidative stress
  • nk cells