The lncRNA Fer1L4 is an adverse prognostic parameter in clear-cell renal-cell carcinoma.

Alexander CoxY TolkachG KristiansenM RitterJ Ellinger

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2020)

Fer1L4 expression significantly correlates with aspects of tumor aggressiveness. Based on this impact on tumor progression and its influence as an independent prognostic factor, Fer1L4 appears to exert properties as an oncogene in ccRCC. As a prognostic tissue biomarker, further functional investigations are warranted to investigate Fer1L4 as a potential therapeutic target.

Keyphrases

prognostic factors
poor prognosis
long non coding rna
emergency department
binding protein
risk assessment
adverse drug