A pilot study of the breath stacking technique associated with respiratory muscle endurance training in patients with amyotrophic lateral sclerosis: videofluoroscopic findings in the upper airway.
Alessandra DorçaMax SarmetEdna Maria de Sena Sousa RochaMurilo Bufaiçal MarraJanae Lyon MillionDenise Sisterolli DinizVinicius MaldanerPublished in: Advances in respiratory medicine (2021)
During the intervention, TR3 showed acute effects in increasing pharyngeal constriction, pharyngeal expansion, retropalatal airspace size, and post-lingual narrowest airway size and is feasible for a larger research program. A clinical trial (NCT04226144) is already being conducted to assess the chronic therapeutic effects of this technique and its impact on the clinical evolution of ALS.
Keyphrases
- amyotrophic lateral sclerosis
- clinical trial
- skeletal muscle
- liver failure
- randomized controlled trial
- drug induced
- neuropathic pain
- respiratory failure
- quality improvement
- study protocol
- high intensity
- open label
- phase ii
- double blind
- aortic dissection
- respiratory tract
- virtual reality
- phase iii
- hepatitis b virus
- spinal cord