Mass Spectrometry based Metabolomics for Small Molecule Metabolites Mining and Confirmation as Potential Biomarkers for Schistosomiasis - Case of the Okavango Delta Communities in Botswana.
Sedireng M Tawana-NdoloMatshediso ZachariahLebotse MolefiNthabiseng PhaladzeKwenga Festus SichilongoPublished in: Expert review of proteomics (2021)
Mass spectrometry metabolomics for schistosomiasis will lead to biomarker discovery for non-invasive human samples. These biomarkers, together with those from other neglected tropical diseases, such as malaria and sleeping sickness, could be incorporated as arrays on a single biosensor chip and inserted into smartphones, in order to improve surveillance, monitoring, and management.
Keyphrases
- mass spectrometry
- small molecule
- liquid chromatography
- gas chromatography
- endothelial cells
- capillary electrophoresis
- high performance liquid chromatography
- protein protein
- high resolution
- high throughput
- public health
- climate change
- ms ms
- gold nanoparticles
- pluripotent stem cells
- induced pluripotent stem cells
- plasmodium falciparum
- circulating tumor cells
- tandem mass spectrometry
- high density
- solid phase extraction