Stem-cell mobilization of healthy sibling donors with pegfilgrastim-A prospective open-label phase II trial (EudraCT no: 2005-004971-39).

Vladan VucinicMadlen JentzschSabine LeibleinEnrica BachYvonne RemaneKai Schulze-ForsterMichael CrossWolfram PönischSebastian SchwindGeorg-Nikolaus FrankeUwe PlatzbeckerDietger Niederwieser

Published in: Transfusion (2021)

The results of this trial showed that stem cell mobilization with pegfilgrastim is a feasible, and attractive option. This is the first trial presenting the kinetics of pegfilgrastim serum levels in healthy donors.

Keyphrases

stem cells
open label
phase iii
phase ii
study protocol

clinical trial
phase ii study
chemotherapy induced
randomized controlled trial

kidney transplantation
placebo controlled
cell therapy
radiation therapy

case report
mesenchymal stem cells
locally advanced
aqueous solution