Next-generation sequencing demonstrates the rarity of short kinase variants specific to quadruple wild-type gastrointestinal stromal tumours.

Newton A C S WongOlivier T GigerRogier Ten HoopenRuth T CaseyKirsty RussellClaire Faulkner

Published in: Journal of clinical pathology (2020)

Short kinase variants which are specific to qWT GISTs are rare and are not universally demonstrated by this whole subgroup. It is therefore possible that the current definition of qWT GIST still covers a heterogenous population.

Keyphrases

copy number
wild type
helicobacter pylori
protein kinase
tyrosine kinase
helicobacter pylori infection
randomized controlled trial
gene expression
dna methylation
circulating tumor
placebo controlled