Adiposity and cardiovascular outcomes in three-year-old children of participants in UPBEAT, an RCT of a complex intervention in pregnant women with obesity.

Kathryn V DalrympleFlorence A S TydemanPaul D TaylorAngela C FlynnMajella O'KeeffeAnnette L BrileyParamala SantoshLouise HayesStephen C RobsonScott M NelsonNaveed SattarMelissa K WhitworthHarriet L MillsClaire SinghPaul T Seed CStatSara L WhiteDeborah A LawlorKeith M GodfreyLucilla Postonnull null

Published in: Pediatric obesity (2020)

This study has demonstrated that an antenatal dietary and physical activity intervention in women with obesity is associated with lower offspring pulse rate and sustained improvement in maternal diet. Whilst larger than previous cohorts, there remains potential for bias from attrition and these findings require validation in future cohorts.

Keyphrases

insulin resistance
weight loss
physical activity
weight gain
randomized controlled trial
metabolic syndrome
pregnant women
high fat diet
high fat diet induced
type diabetes
birth weight
body mass index
blood pressure
adipose tissue
current status
preterm birth
risk assessment
human health